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Croda International Plc
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Croda International Plc
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Biotium
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Matreya LLC
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Federation of European Neuroscience Societies
c6-nbd-ceramide ![]() C6 Nbd Ceramide, supplied by Federation of European Neuroscience Societies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/c6+nbd+ceramide/c6+nbd+ceramide/pm10606729-3-11-21 Average 90 stars, based on 1 article reviews
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SCHOTT
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ApexBio
c6-nbd-ceramide n-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-d-erythro-sphingosine ![]() C6 Nbd Ceramide N {6 [(7 Nitro 2 1,3 Benzoxadiazol 4 Yl)amino]Hexanoyl} D Erythro Sphingosine, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/c6+nbd+ceramide/c6+nbd+ceramide+n++6+++7+nitro+2+1+3+benzoxadiazol+4+yl+amino+hexanoyl++d+erythro+sphingosine/10__1128_slash_mbio__01467___19-306-30-32 Average 90 stars, based on 1 article reviews
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Image Search Results
Journal: mBio
Article Title: Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids
doi: 10.1128/mBio.00647-15
Figure Lengend Snippet: Measurements of sphingolipids upon treatment with BHBM. (a) Thin-layer chromatography analysis of sphingolipids (see diagram) isolated from untreated or BHBM-treated C. neoformans cells after in vivo labeling with [ 3 H]palmitate ( 3 H-Palm). (b to h) Lipid analysis by LC-MS. (b) C18 hydroxy (Δ8) 9 methyl-glucosylceramide (GlcCer); (c) C18 dihydroceramide (C18 dhCer); (d) sphingosine and dihydrosphingosine (SPHs); (e) sphingosine-1-phosphate and dihydrosphingosine-1-phosphate (SPH-1-P); (f) C18 hydroxyceramide (C18 OH-Cer); (g) C18 hydroxy Δ8-ceramide (C18 OH-Δ8-Cer); and (h) C18 hydroxy Δ8, 9 methyl-ceramide (C18 OH-Δ8, 9Me-Cer). Values that are significantly different are indicated as follows: *, P < 0.05 comparing treated to untreated (no drug). Statistical analysis was performed using analysis of variance (ANOVA) test. Statistical significance is accepted at a P value of <0.05. Data were compiled from three independent experiments.
Article Snippet: Fluorescence intensity of yeasts labeled with
Techniques: Thin Layer Chromatography, Isolation, In Vivo, Labeling, Liquid Chromatography with Mass Spectroscopy
Journal: mBio
Article Title: Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids
doi: 10.1128/mBio.00647-15
Figure Lengend Snippet: Effect of BHBM on Golgi morphology in C. neoformans and yeast-to-hyphal differentiation in C. albicans . (A) Control or BHBM-treated cells were stained with NBD C6-ceramide (Golgi and Golgi-derived compartments, green fluorescence). DIC, differential interference contrast; NBD-Cer, NBD 6-ceramide. Bars, 5 µm. (B) FACS analysis shows NBD C6-ceramide accumulation in C. neoformans . The gray histogram corresponds to C. neoformans yeast in the absence of NBD C6-ceramide. CT, control (no BHBM treatment). (C) Percentage of yeast and hyphal forms under control conditions and after BHBM treatment. Statistical analysis was performed using analysis of variance (ANOVA) test. Statistical significance is accepted at a P value of <0.05. The images in panels A and B are representative of three separate experiments. The data in panel C were compiled from three independent experiments.
Article Snippet: Fluorescence intensity of yeasts labeled with
Techniques: Staining, Derivative Assay, Fluorescence